Schmidt, B., Hinman, J. R., Jacobson, T. K., Szkudlarek, E., Argraves, M., Escabí, M. A., & Markus, E. J. (2013). Dissociation between dorsal and ventral hippocampal theta oscillations during decision-making. The Journal of Neuroscience, 33(14), 6212–24. [PDF]
Jacobson, T. K., Howe, M. D., Schmidt, B., Hinman, J. R., Escabí, M. A., & Markus, E. J. (2013). Hippocampal theta, gamma, and theta-gamma coupling: effects of aging, environmental change, and cholinergic activation. Journal of Neurophysiology, 109(7), 1852–65. [PDF]
Schmidt, B., Papale, A., Redish, A. D., & Markus, E. J. (2013). Conflict between place and response navigation strategies: Effects on vicarious trial and error (VTE) behaviors. Learning & Memory, 20(3), 130–8. [PDF]
Schmidt, B., Satvat, E., Argraves, M., Markus, E. J., & Marrone, D. F. (2012). Cognitive demands induce selective hippocampal reorganization: Arc expression in a place and response task. Hippocampus, 22(11), 2114–26. [PDF]
Penley, S. C., Hinman, J. R., Sabolek, H. R., Escabí, M. A., Markus, E. J., & Chrobak, J. J. (2012). Theta and gamma coherence across the septotemporal axis during distinct behavioral states. Hippocampus, 22(5), 1164–75. [PDF]
Schmidt, B., Marrone, D. F., & Markus, E. J. (2012). Disambiguating the similar: The dentate gyrus and pattern separation. Behavioural Brain Research, 226(1), 56–65. [PDF]
Jacobson, T. K., Gruenbaum, B. F., & Markus, E. J. (2012). Extensive training and hippocampus or striatum lesions: effect on place and response strategies. Physiology & Behavior, 105(3), 645–52. [PDF]
Satvat, E., Schmidt, B., Argraves, M., Marrone, D. F., & Markus, E. J. (2011). Changes in task demands alter the pattern of zif268 expression in the dentate gyrus. The Journal of Neuroscience, 31(19), 7163–7167. [PDF]
Sink, K. S., Segovia, K. N., Collins, L. E., Markus, E. J., Vemuri, V. K., Makriyannis, A. & Salamone, J. D. (2010). The CB1 inverse agonist AM251, but not the CB1 antagonist AM4113, enhances retention of contextual fear conditioning in rats. Pharmacology, Biochemistry and Behavior, 95(4), 479–84. [PDF]
Swetter, B. J., Fitch, R. H., & Markus, E. J. (2010). Age-related decline in auditory plasticity: experience dependent changes in gap detection as measured by prepulse inhibition in young and aged rats. Behavioral Neuroscience, 124(3), 370–80. [PDF]
Sink, K. S., Segovia, K. N., Sink, J., Randall, P. A, Collins, L. E., Correa, M., Markus, E. J., Vemuri, V. K., Makriyannis, A., Salamone, J. D. (2010). Potential anxiogenic effects of cannabinoid CB1 receptor antagonists/inverse agonists in rats: comparisons between AM4113, AM251, and the benzodiazepine inverse agonist FG-7142. European Neuropsychopharmacology, 20(2), 112–22. [PDF]
Schmidt, B., Jacobson, T. K., & Markus, E. (2009). Hippocampal and striatal dependent navigation: sex differences are limited to acquisition. Hormones and Behavior, 56(2), 199–205. [PDF]
Hodges, D. B., Lindner, M. D., Hogan, J. B., Jones, K. M., & Markus, E. J. (2009). Scopolamine induced deficits in a battery of rat cognitive tests: comparisons of sensitivity and specificity. Behavioural Pharmacology, 20(3), 237–51. [PDF]
Sabolek, H. R., Penley, S. C., Hinman, J. R., Bunce, J. G., Markus, E. J., Escabi, M., & Chrobak, J. J. (2009). Theta and gamma coherence along the septotemporal axis of the hippocampus. Journal of Neurophysiology, 101(3), 1192–200. [PDF]
Oler, J. A., Penley, S. C., Sava, S., & Markus, E. J. (2008). Does the dorsal hippocampus process navigational routes or behavioral context? A single-unit analysis. European Journal of Neuroscience, 28(4), 802–12. [PDF]
Sava, S., & Markus, E. J. (2008). Activation of the medial septum reverses age-related hippocampal encoding deficits: a place field analysis. The Journal of Neuroscience, 28(8), 1841–53. [PDF]
Tropp Sneider, J., Chrobak, J., Quirk, M., Oler, J., & Markus, E. (2006). Differential behavioral state-dependence in the burst properties of CA3 and CA1 neurons. Neuroscience, 141(4), 1665–77. [PDF]
Oler, J. A., Ramos, R. L., Penley, S. C., & Markus, E. J. (2005). Hippocampal and amygdalar involvement in discriminatory place learning. Neuroscience, 132(1), 1–12. [PDF]
Tropp, J., Figueiredo, C. M., & Markus, E. J. (2005). Stability of hippocampal place cell activity across the rat estrous cycle. Hippocampus, 15(2), 154–65. [PDF]
Sava, S., & Markus, E. J. (2005). Intramaze cue utilization in the water maze: effects of sex and estrous cycle in rats. Hormones and Behavior, 48(1), 23–33. [PDF]
Astur, R. S., Tropp, J., Sava, S., Constable, R. T., & Markus, E. J. (2004). Sex differences and correlations in a virtual Morris water task, a virtual radial arm maze, and mental rotation. Behavioural Brain Research, 151(1-2), 103–15. [PDF]
Tropp, J., & Markus, E. J. (2001). Effects of mild food deprivation on the estrous cycle of rats. Physiology and Behavior, 73(September 2000), 553–559. [PDF]
Tropp, J., & Markus, E. J. (2001). Sex differences in the dynamics of cue utilization and exploratory behavior. Behavioural Brain Research, 119(2), 143–154. [PDF]
Oler, J., & Markus, E. (2000). Age-related deficits in the ability to encode contextual change: A place cell analysis. Hippocampus, 10(3), 338–50. [PDF]
Oler, J. A., & Markus, E. J. (2000). Age-related deficits in episodic memory may result from decreased responsiveness of hippocampal place cells to changes in context. Annals of the New York Academy of Sciences, 911(1), 465–470. [PDF]
Ward, M. T., Oler, J. A., & Markus, E. J. (1999). Hippocampal dysfunction during aging II: Deficits on the radial-arm maze. Neurobiology of Aging, 20, 373–380. [PDF]
Ward, M. T., Oler, J. A., & Markus, E. J. (1999). Hippocampal dysfunction during aging I: Deficits in memory consolidation. Neurobiology of Aging, 20, 363–372. [PDF]
Oler, J., & Markus, E. (1998). Age-related deficits on the radial maze and in fear conditioning: Hippocampal processing and consolidation. Hippocampus, 8(4), 402–415. [PDF]
Markus, E. J., & Zecevic, M. (1997). Sex differences and estrous cycle changes in hippocampus-dependent fear conditioning. Psychobiology, 25(3), 246–252. [PDF]
Markus, E., & Qin, Y. (1995). Interactions between location and task affect the spatial and directional firing of hippocampal neurons. The Journal of Neuroscience, 15(November), 7079–7094. [PDF]
Markus, E. J., Petit, T. L., Leboutillier, J. C., & Brooks, W. J. (1994). Morphological Characteristics of the Synapse and Their Relationship to Synaptic Type : An Electron Microscopic Examination of the Neocortex and Hippocampus of the Rat. Synapse, (17), 65–68. [PDF]
Markus, E. J., Barnes, C. A., McNaughton, B. L., Gladden, V. L., & Skaggs, W. E. (1994). Spatial information content and reliability of hippocampal CA1 neurons: Effects of visual input. Hippocampus, 4(4), 410–21. [PDF]
Book Chapters:
Skaggs W.E., McNaughton B.L., Gothard K.M., and Markus E.J. (1993). An information-theoretic approach to deciphering the hippocampal code. In Advances in Neural Information Processing Systems 5, S.J. Hanson, J.D. Cowan, and C.L. Giles eds, Morgan Kaufmann Pub., California, pp 1030-1037.
Ivy G.O., MacLeod C.M., Petit T.L. and Markus E.J. (1992). A Physiological framework for perceptual and cognitive changes in aging. In Handbook of Aging and Cognition, Craik F.I.M. and T.A. Salthouse eds., Lawrence Erlbaum Assoc., pp 273-314
Petit T.L., and Markus E.J. (1987). The cellular basis of learning and memory: The anatomical sequel to neuronal use. In Neural Plasticity, Learning and Memory, Milgram NW, MacLeod C, and Petit TL (Eds.), Academic Press, N.Y., pp 87-124.
Abstracts:
Nicholas E Paul (g) and Etan J Markus (2012). Dissociating the effects of caffeine on encoding, consolidation, and retrieval using a delayed-match-to-place radial water maze task. SFN
Amanda Swanson (g), Sharon Casavant (u), Greg Newman (u), Stephen King, Diano F. Marrone, Etan J. Markus (2012). Regional hippocampal Arc expression during a change of emotional context but no change of trajectory. SFN
Schmidt BJ (g), Papale AE, Markus EJ, Redish DA (2012). Vicarious trial and error (VTE) behaviors on a task that puts place and response strategies in conflict. SFN
Grella SL, Schmidt BJ (g), Satvat E, Markus EJ, Marrone DF (2012). Prefrontal Arc expression during a spatial and non-spatial navigation task with an identical trajectory. SFN
Paul NE (g), Jacobson, T.K (g), Pallay S. (u), Fink JJ (u), Schmidt B (g), Chrobak JJ, Markus EJ (2011). Differential effects of the anticholinesterase physostigmine and the adenosine antagonist caffeine on memory encoding and retrieval in aged rats: interventions to reduce proactive interference. Society for Neuroscience Abstracts 410.17
Markus EJ, Schmidt B (g), Booker A, Chen F, Argraves M (u), Szkudlarek E (u), Loturco JJ (2011). Effects of hippocampal arc knockdown on hippocampal dependent/independent learning. Society for Neuroscience Abstracts 410.18
Schmidt, B, Argraves M., Szkudlarek E, Hinman JR, Jacobson, T.K, Escabi M, Markus EJ (2011). Theta-gamma modulation along the septotemporal axis during a place and response task. Society for Neuroscience Abstracts 938.10
Jacobson, T.K (g), Howe MD (u), Schmidt B (g), Hinman JR, Bohannon S (u), Mastro KJ (u), Escabie M, Markus EJ (2011). Hippocampal oscillations in young and aged rats: Response to altered environments. Society for Neuroscience Abstracts 938.20
Jacobson TK (g), Howe MD (u), Bohannon S (u), Markus EJ (2010). Hippocampal theta activity in young and aged rats: Effects of a modified environment and Physostigmine. SFN 203.13
Schmidt B (g), Forgette L. (u), Escabi M, Markus EJ (2010). Theta and gamma oscillations in the hippocampus, striatum, and prefrontal cortex during a place and response task. SFN 203.14
Swetter BJ (g), Fitch R, Markus EJ (2010). Aging and correlations across visual, auditory and cognitive processing in F344 rats. SFN 204.1
Markus EJ, Schmidt B (g), Satvat E., Lamontagne T (u), Som C (u), Marrone D (2010). Regional hippocampal expression of IEGs during a spatial and non-spatial navigation task with an identical trajectory. SFN 709.8
Jacobson TK (g). Gruenbaum BF (u), Markus EJ (2010). Multiple Memory Systems: A novel navigation task investigates hippocampus- and striatal- memory. APS Annual Convention, May 27 – 30, Boston
Swetter BJ, R.H. Fitch, Markus EJ. (2010). Correlation Between Rats’ Visual, Auditory, and Cognitive Processing During Aging. APS Annual Convention, May 27 – 30, Boston.
Schmidt B, Forgette L, Markus EJ. (2010). Lfp Examination in Hippocampus and Striatum During a Place and Response Task APS Annual Convention, May 27 – 30, Boston.
Penley S. C. Hinman, J. R. Escabi, M. A. Markus, E. J. Chroback, J. J. (2009). Salience of environmental novelty: Theta power, frequency and coherence within the hippocampus and entorhinal cortex SFN 192.28
Jacobson TK (g). Gruenbaum BF (u), Markus EJ (2009). New insight into the involvement of hippocampus and striatum during navigation: An analysis of errors on a dissociative maze task. SFN 679.9
Schmidt B (g), Satvat E., Argraves M. (u), Marrone D.,Markus, E. J. (2009). Arc expression throughout the hippocampus: Contrasting spatial and non-spatial navigation with an identical trajectory. SFN 679.10
Swetter BJ (g), R.H. Fitch, Markus EJ (2009). Age related changes in plasticity of auditory and visual processing. SFN 891.14
Jacobson TK (g), Gruenbaum B (u), Markus EJ (2008). Multiple memory systems in the brain: The role of the hippocampus and striatum during a dissociative maze task. SFN Abstracts 389.1
Schmidt B (g), Hinman JR, Penley SC (g), Jacobson TK (g), Ciurylo E (u), Zhang E (u), Esacabi MA & Markus EJ (2008) Local field potentials in the hippocampus, striatum, and nucleus accumbens during a place and response task. SFN Abstracts 389.3
Markus EJ, Jacobson T (g), Zhang E (u), Liu J (u), Novak E, Crowley-Miano M (u), Fitch RH (2008). Interrelation between visual, auditory and spatial processing performance in aged rats. SFN Abstracts 389.2
Penley SC, Hinman JR, Escabi MA, Markus EJ, Chrobak JJ (2008). The Effects of Novelty and Aging on the Coherence of Theta and Gamma in the Hippocampus and Entorhinal Cortex. SFN Abstracts 879.3
Sava S.(g), Jacobson TK (g), Markus EJ (2008). Cholinergic system activation reverses age—related hippocampal encoding deficits: A place field analysis. American Aging Association Conference, Boulder CO. (29 May-2 June)
B. Schmidt (g), S. C. Penley (g), J. R. Hinman, T. K. Jacobson (g), J. Fairchild (U), B. Gruenbaum (U), M.A. Escabi & E. J. Markus. (2007). Oscillations of local field potentials in the rat dorsal hippocampus, dorsal striatum, and nucleus accumbens: Comparing place & response trials. SFN Abstractss 640.7
J. Hwang, D. Butler, S. Ryzhikov, H. Tarpada, A. Tarpada, E.J. Markus, J.J. Chrobak, D.A. Karanian, and B.A. Bahr (2007). Lysosomal enhancement promotes functional recovery in the APPswe/PS1dE9 mouse model of Alzheimer’s Disease. SFN Abstracts 157.12
Cleaver C (U), Hill CA, Zhang E (U), Fitch RH & Markus EJ. (2007). Effects of early brain damage on cross modal sensory processing. SFN Abstracts 594.8
T.K. Jacobson (g), G.J. Peters (U), B. Gruenbaum (U), E.J. Markus (2007). Septal modulation of hippocampal processing: Age-related effects of carbachol on the development and maintenance of CA1 and CA3 place fields SFN Abstracts 640.8
S. Sava (g), G. J. Peters (U), E. J. Markus (2007). Effects of intraseptal carbachol on bursts properties of CA1 pyramidal neurons. SFN Abstracts 640.9
S. C. Penley (g), J. G. Bunce, M. A. Escabi, E. M. Markus, J. J. Chrobak (2007). Theta coherence varies across areal subdivisions of the entorhinal cortex and between hippocampal and entorhinal regions. SFN abstracts 305.9
Jacobson TK, Cleaver CA, Schmidt B, & Markus EJ (2006). Competition and coordination between the hippocampus and striatum. SFN abstracts 266.9
Schmidt B, Jacobson TK & Markus EJ (2006). Sex differences in competition and coordination between the hippocampus and striatum. SFN abstracts 266.10
Sava S., Peters GJ, & Markus EJ (2006). Septal modulation of hippocampal single unit activity: Age related effects of carbachol on the development and maintenance of place fields. SFN abstracts 371.21
Hinman JR, Brandon MP, Sava S, & Markus EJ (2006). Examining the orthogonality of hippocampal place cells across environments. SFN abstracts 371.20
Penley SC, Sabolek HR, Escabi MA, Markus EJ and Chrobak JJ (2006). Theta and Gamma Coherence Along the Septo-Temporal Axis of the Hippocampus and Entorhinal Cortex during REM Sleep, Maze Running, and Physostigmine Treatment in Rats. SFN abstracts 751.9
Hodges DB, Lindner MD, Hogan JB, & Markus EJ (2006). Reliability of individual performance on, and across “hippocampal tasks” SFN abstracts 162.15
AJ Purton, R.S. Astur, M. Zaniewski, E.J. Markus (2005). Examining human navigation strategies on a virtual maze. Society for Neurosci. Abstracts #192.2
Hodges Jr. DB, Lindner MD, Hogan JB, & Markus EJ (2005). Low doses of scopolamine disrupt attention and other non-mnemonic behaviors. Society for Neurosci. Abstracts #881.3
SC Penley, HR Sabolek, MA Escabi, EJ Markus and JJ Chrobak (2005). Theta Range Activity Along the Septo-Temporal Axis of the Hippocampus and Entorhinal Cortex in the Behaving Rat. Society for Neurosci. Abstracts #73.1
S. Sava, E.J. Markus (2005). Medial septal modulation of hippocampal single unit activity: effects of carbachol and lidocaine on the development and maintenance of place fields. Society for Neurosci. Abstracts #73.5
EJ. Markus, D Velednitski, A Betz, L Madson, JD. Salamone (2005). The anticholinesterase tacrine suppresses ultrasonic vocalizations within the same dose range that induces tremulous jaw movements: Possible implications for studies related to parkinsonism. Society for Neurosci. Abstracts #665.9
S.Sava, E.J.Markus (2004). Place field properties and burst characteristics of hippocampal pyramidal neurons after intraseptal scopolamine infusion SFN 209.4
J.Tropp, C.M.Figueiredo; E.J.Markus (2004). Hippocampal place cells are relatively stable across the rat estrous cycle. SFN 209.5
S.C.Penley, H.R.Sabolek; E.J.Markus; J.J.Chrobak (2004). Synchronization in hippocampal formation ( entorhinal cortex and hippocampus ) of the awake – behaving rat. SFN 897.6
J.Chen, M.M.McClure; R.H.Fitch; E.J.Markus (2004). Cross modal sensory processing assessments in rodent models of early brain damage. SFN 913.3
E.J.Markus, J.Tropp, J.J.Chrobak, M.C.Quirk, J.A.Oler (2004). A comparison of hippocampal CA1 and CA3 burst properties in behaving animals. SFN 10007.9
J.A.Oler; S.Penley; R.L.Ramos; E.J.Markus (2003) Hippocampal Place Cell Activity During Context-Dependent Discriminative Place Aversion. Society for Neurosci. Abstracts #29
S. Sava, J. Chen, AM. Peiffer, RH. Fitch, E.J. Markus. (2003). Testing visual acuity in aged rats. Society for Neurosci. Abstracts #29
S. Sava, R.S. Astur, E.J. Markus. (2002). Spatial ability in rodents and humans: Cue utilization, sex differences and the influence of the natural hormone state. Society for Neurosci. Abstracts #28
J. Tropp, M.C. Quirk, J.A. Oler, E.J. Markus (2002). Hippocampal place cells across the rat estrous cycle. Society for Neurosci. Abstracts #28
S. Sava, J. Tropp, R.S. Astur, R.T. Constable, & E.J. Markus (June, 2002). Sex differences and behavioral correlates in mental rotation and virtual maze tasks. Annual Meeting of the Society for Behavioral Neuroendocrinology at Amherst College, MA.
J.Tropp; S.Sava; R.S.Astur; R.T.Constable; A.Shea; E.J.Markus (2001). Sex differences and behavioral correlates in a virtual 8-arm maze, a virtual Morris water task, and in mental rotation. Neurosci. Abstracts 27: #74.11
J.A.Oler; S.Penley; R.L.Ramos; E.J.Markus (2001). The effects of lesions to the hippocampus and amygdala on auditory context discrimination and place learning. Neurosci. Abstracts 27: #853.14
R.L.Ramos; S.Sava; E.J.Markus (2001). Effects of bicuculline-induced GABA antagonism on consolidation of fear memory. Neurosci. Abstracts 27: #853.15
Tropp, J. & Markus, E. J. (2000). Effects of mild food deprivation in four rat strains. Joint Meeting of the VIth International Conference on Hormones, Brain & Behavior and the Society for Behavioral Neuroendocrinology, 6: 181.
E.J. Markus; C.R. Stoelzel; R. Ramos; M.T. Ward; J.A. Oler (2000). To consolidate or not to consolidate: Is spaced-learning the answer? Neurosci. Abstracts #265.16 26: 713
Tropp, J. & Markus, E. J. (2000). Effects of mild food deprivation on the estrous cycle in female rats. Neurosci. Abstracts #265.15 26: 713
Oler JA., and Markus EJ. (2000). Age-related deficits in episodic memory may result from a decreased responsiveness of hippocampal place cells to changes in context. Annuals of the New York Academy of Sciences.
Oler JA, and Markus EJ (1999). Hippocampal place cells are less responsive to changes in task demands in old rats. Neurosci. Abstracts 25:1627
Tropp J., Cunningham M.A. & Markus E.J. (1999). Dynamics of cue utilization: Differences between males and females. Neurosci. Abstracts 25: 1627
Markus E.J and Tropp J. (1999). Strategies for assessing the effects of sex and estrous cycle on hippocampal ability. Neurosci. Abstracts 25: 1627
Stoelzel C.R., Stravnezer AJ, Marchillo S, Carlson J., Denenber VH, Markus EJ (1999). A reference water maze task comparable in difficulty to the Morris water maze: Effects of age and hippocampal lesions. Neurosci. Abstracts 25: 1627
Ward MT, Oler JA, Stoelzel CR, and Markus EJ (1999). Age and hippocampal lesion effects on a cued reference memory task. Neurosci. Abstracts 25: 1627
Tropp J. and Markus EJ (1999). Sex differences in the dynamics of cue utilization. Society for Behavioral Neuroendocrinology Annual Meeting, Univ. of Virginia (June 26-30, 1999)
Stoelzel CR, Ward MT, and Markus EJ (1998). The effect of hippocampal lesions on old and young rats on spatial working and reference memory components of the radial arm maze. Neurosci. Abstracts 24: 929
Markus EJ, Sachs BD, Cooper C, Bachand JP, and Denenberg VH (1998). Activity levels, hippocampal function and ejaculation ex-copula: A comparison of F344 and Long Evans hooded rats. Neurosci. Abstracts 24: 929
Ward MT, Stoelzel CR, Oler JA, and Markus EJ (1998). Hippocampal memory deficits in aged rats may result from impaired consolidation. Neurosci. Abstracts 24: 929
Oler J.A. and Markus E.J. (1997). Aging and the hippocampus: Impairments on fear conditioning and radial maze tasks. Neurosci. Abstracts 1608
Brown J.E., Hunt K., and Markus E.J. (1997). Fear conditioning: The relative importance of local and distal spatial contextual environments. Neurosci. Abstracts 1609
Markus E.J., Zecevic M., and Anderson ML. (1996). Contextual fear conditioning across the estrous cycle. Neurosci. Abstracts 22: 1134.
Markus E.J., Qin Y., McNaughton B.L., Barnes C.A. (1995). Hippocampal place cell encoding of the environment: Insights from simultaneous recording of multiple single units. Annals of Biomedical Engineering 23: S-86.
McNaughton B.L., Barnes C.A., Gothard K., Skaggs W., Wilson M., Qin Y., Markus E.J., Kudrimoti H., Suster M., Gerrard J., D’Monte R., and Stengel C. (1995). Rapid encoding of both spatial and non-spatial representations in hippocampal ensembles, and their reactivation during off-line processing. Int. Symp. Perception, Memory and Emotion: Frontier in Neurosci., July 3-7, 1995, Toyama, Japan.
Qin Y., Markus E.J., McNaughton B.L., and Barnes C.A. Hippocampal place fields change with navigational context. Neurosci. Abstracts, 1994, 20:1207
Stoehr J.D., Markus E.J., Nadel L., and Wenk G.L. Effects of post-training intrahippocampal and amygdaloid injections of scopolamine on contextual and cued-fear conditioning. Neurosci. Abstracts, 1994, 20:149
Markus E.J., Qin Y., McNaughton B.L., and Barnes C.A. Place fields are affected by behavioral and spatial constraints. Cog. Neurosci. Soc., 1994